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Zolpidem, sold under the brand name Ambien, among others, is a medication primarily used for the short term treatment of sleeping problems.It decreases the time to sleep onset by about 15 minutes and at larger doses helps people stay asleep longer.
The recommended dose was decreased in 2013 due to next-morning impairment. While flumazenil can reverse zolpidem’s effects, usually supportive care is all that is recommended in overdose.
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Zolpidem is a nonbenzodiazepine and hypnotic of the imidazopyridine class. Zolpidem is a type A GABA receptor agonist. It works by increasing GABA effects in the central nervous system by binding to GABAA receptors at the same location as benzodiazepines.
Sedative hypnotic drugs including eszopiclone are more commonly prescribed to the elderly than to younger patients despite benefits of medication being generally unimpressive.